First off it's a very nice game and I never thought, that low money could be worth that much entertainment... okay enough flattering now...
There's some bug when Guybrush moves on the map between two spots. If I press escape and get to the menu and switch back, Guybrush is not moving anymore. That way he won't reach his target. I thought clicking on a spot would solve the problem but I can't click on anything. Solution of mine: possibility to change targets whenever I want to.
Now some little spoiler according to a puzzle: You use that ancient weather vane at the well then Guybrush moves around the well instead of being teleported instantly to that location. It takes some time and is also irritating for me if I don't see where he stood in the "cinematic" scene and which direction to go.
Sometimes Guybrush jumped from one spot to another. For example in Deep Gut's house, I stand near the chair, looked at something and then he's in front of the altar.
A little cosmetic issue: I noticed Guybrush sometimes running with this left arm down and only the right one swinging. Any good reason for that?
I just wanna make it better, nothing else. Maybe you could solve one or another problem.