Whenever I play TMI, Guybrush and all of the animated characters glitch. Many of the planes (in geometric terms) which make up the polygons in the bodies and faces "flash". They appear and disappear at random. I get to see glimpses of Guybrush's eyeballs through the holes made by the missing planes (if that makes any sense).
I would take a screenshot, but whenever I record it with FRAPS (even at the lowest FRAPS frame rate and without recording sound) the graphics look normal, and all of the polygons are solid again and no random planes disappear (although I think frame rate drops a little).
The picture included in the attachments has 3 pictures:
1) a picture of Guybrush as I see him in gameplay.
2) Another picture of him. Ugly, isn't he?
3) A picture I took while I was in MS Paint making this jpg. When I use FRAPS to record TMI (or apparently stop using TMI while in windowed mode), Guybrush et all look normal.