Wohoo! Xplay loved it! :D They mentioned that the clicking to find things is tedious (I don't think they really played it very much), but that the humor was absolutely fantastic! The two hosts were smiling when the review was done, so they seemed to like it too.
They mentioned how unlike Half Life 2's episodes, which are being released very slowly, Sam & Max is being released monthly and following schedule. Overall they gave it a great review.
The only minor fault was the item and clicking part, but that's what adventure games are all about. I don't think there's enough of it personally. It probably reflects mainstream opinions of it though, since people like fast paced action.