Okay, I waited until Sam and Max Season One was released on CD (I enjoy having a CD), I picked up a copy at my local Best Buy.
Installing it went perfectly fine until I started to play. SecuRom said that I was using a burnt CD, but obviously I wasn't (I can scan a picture of my cd or receipt if you want). I followed the instructions on their FAQ but it was for Windows XP not Vista. So I emailed them and waited, hopefully they would reply by Thanksgiving (I gave them a week). They didn't so I came here.
I've tried to find a nocd crack (There wasn't any I could find), then I tried mounting an image of the cd with Daemon Tools but that didn't work. I haven't really need to so this with any other game because I don't mind having a cd in the cd drive, so I really don't know what I am doing with the somewhat shady circumventions.
Thanks, I really just want to play the game.