Originally Lilly from the game and Lilly Caul from the comics/book were supposed to be the same person, but that was later changed.
With them now being two completely different characters, what should happen with Lilly from the game? As it stands, her fate is a complete unknown.
Should she return in the sequel? Should she not return as a character, but we discover her fate in some other fashion? Or should her ultimate fate be left a mystery, with no one ever knowing whether she lives or dies following either being ditched on the side of the road, or taking off alone in that RV?