I hope that they feature:
The games from the SB site in Sam and Max form.
Different skins like the SB homepage for the main menu / Save-load, Options, Exit bit.
A puzzle like Sam and Max with the multiple options, with these requirements:
A puzzle which requires you to write an email to SB which makes him do something to continue the story.
A puzzle where you draw your own Trogdor.
Another timetravel episode. I know it's only just been done in S & M, but I want to play as Strongbadiophage.
Some Cheat Commandos and Teen Girl Squad references.
That's it. Do those, and this SB game is easily the most wanted game(s) of this year for me.