I've never heard of these characters before. Maybe it's just me or they generally aren't this well known in germany, which to some degree must be the case as otherwise they wouldn't be introduce so well. Anyway i had a look at the characters and my first thought was this looks just disgusting. It's almost the opposite of what i like. But whilst saying so the videos also had a certain charme, it's both distracting and interesting.
So i went to youtube and watched a few videos which they have online and whilst not everything was something to laugh, i liked the concept behind it and three of the videos were really funny (video games, dragon, can't remember the third). So i think you can get used to this look to a certain degree but as soon as the humour is out it leaves at least me in a quite distracting world. It heavily depends on how funny/interesting these games will be designed. It's hard to imagine moments, like in Sam&Max, were you just sit back and enjoy the atmosphere in a certain location for a while. Other game aspects than the gfx have to do the work here on their own.