The best thing they could do if they were to remake 'escape' would be to recast the voice of Herman Toothrot. If Escape had only 1 failing then it was the voice of this character.
The guy who did the voice clearly looked at the art and thought "Hmmm... This guy looks like one of those 'old coots' from black and white westerns set in the gold rush era, to me... I think I'll make him sound like one, too!".
Even if nobody felt comfortable going with a more traditional euro-accent they could have at least gone for a generic US accent, like Guybrush's. (It sounds generic to me, sorry to anybody from the US who might have taken some offense to this)