I'm Stuart, a full time composer / music producer from the UK and I love Sam n Max, I've replayed hit the road 100s of times (and I play it even more now I have a GP2X :-)
Great start to the new series - and its great to see a proper adventure game, however the one niggling annoyance was the amount / type of compression applied to the speech.
The speech is compressed to such a degree that it is very noticeable especially on s's and female voices. I don’t think most people would mind a longer download time in order to get full quality speech. Maybe offer 2 versions?