There's a minor glitch in all the episodes that will only occur on Windows XP x64. When I enter the office, I hear no music playing. In my Windows XP 32-bit the sound works fine. This occurs in some other locations as well, but in others not. When I enter Sybils the music will play, but when I enter Bosco's suddenly the music is gone. The music comes back when I walk out on the street.
I am not sure in what extent the game supports Windows XP x64, since it says only Windows XP on the system requirements, but I am sure you can use this information for something no matter :)
Of course, this is nothing serious. I just wanted to report it just in case.