So I found that Sam and Max isn't the only one in pop culture to bear their names.
For example, Todd McFarlane's Sam and Twitch
Twitch's name is Maximillian. They're cops. I don't read Spawn, so I don't know any further than that.
And then of course, there's this:
I watched this movie years ago, so I couldn't remember much about it, but I know from wikipedia that Dustin Hoffman's character's name is Max, and John Travolta's character's name is Sam.
Any other examples?