I noticed that there is a legend that "Four Is Death". According to TV Tropes, "In Chinese Language, Japanese Language, and Korean Language, the words for "Four" and "Death", despite being written differently, are pronounced similarly (somewhat like "sì" in Mandarin, "shi" in Japanese, "sa" in Korean, and "sei" in Cantonese). As a cultural trope, Asian works of media tend to treat the number the same way Western writers treat the number 13 (except 13 isn't half a letter away from "death"). As a similar point of reference, point building floors and apartments are (mis)numbered accordingly to avoid the number, and some Japanese people prefer to say "yon" (another word for four) instead of "shi"."
I also noticed that in Tales of Monkey Island, four seems to be the very embodiment of death in Chapter 4, even though it may be a coincidence. As a result, I added Tales to the Four Is Death trope, and "Four Is Death" to the Tales Of Monkey Island trope if you want to see both. I wondered if the folks at Telltale have borrowed some "four is death" idea from Eastern culture while working on ToMI, especially Chapter 4.