Here's my own idea for an adaption
The Sandman Comic, written by Neil Gaiman.
I think it'd make a good Adventure Game Because the title character was often more of an "observer" than a hero, therefore he needn't be the game's main character (you wouldn't want the lead protagonist to have his powers in any case, you'd find yourself constantly asking yourself why he simply doesn't use them to solve his various situations when you know there wouldn't be much of a game if he did). Ideal characters for this role might include one (or more than one) of the reoccurring characters from "the dreaming" (the dream world) or the real world or an original character from either.
A character from the real world would probably be somebody who stumbles into a situation involving some entity, previously believed to be mythological (whether they know it or not), then having to undertake a journey which will lead them across the paths of other ethereal or (simply extremely powerful) beings, eventually crossing into Morpheus' (The Sandman's) domain.
Ideally I'd want an original story based on the comics set in the world(s) of the Sandman stories (though probably disregarding any connection to the DC universe and justice league characters who appeared in the first few stories). It can be after the events of the original series (with Morpheus' successor in place as the new king of the dreaming) or simultaneously; events that might have occurred at the same time as the stories featured in the comics that were never mentioned, though nonetheless involved the dreaming and characters from the Sandman).
The comic had some of the best art work I've seen in any comic with stunning backdrops which almost overshadowed the foreground. A game with similar beauty is bound to be noticed. (I know 'gameplay > graphics', but I still think adventure games can afford to be beautiful).
Licensing mightn't be too difficult; the comic drew to a close over 12 years ago and will have been forgotten (to an extent). (There was talk of a movie but all attempts have failed due to various disagreements between directors, producers and Mr. Gaiman himself).
I think one of the biggest problems would be the consent of Mr. Gaiman. He regards 'the Sandman', possibly, as his Magnum Opus and expects high standards to be maintained. For example, he referred to the last script sent to him by Warner Bros as "...not only the worst Sandman script I've ever seen, but quite easily the worst script I've ever read." 2 Years ago, when asked about a sand man movie, he had this to say; "I'd rather see no Sandman movie made than a bad Sandman movie. But I feel like the time for a Sandman movie is coming soon. We need someone who has the same obsession with the source material as Peter Jackson had with Lord of the Rings or Sam Raimi had with Spider-Man." (off-topic; was Sam Raimi obsessed with spider man? Because those movies SUCKED!)
I imagine he'd want to see such high standards maintained with this title if it was adapted to ANY medium.