I'm another guy who doesn't like the idea of a sequel, but if there HAD to be one it'd have to be about a new set of characters with maybe a few cameos like Glottis. Or maybe just new game about Glottis. The idea of me seeing how Manny and so lived their actual LIVES seems wrong as the shady pasts of these people is what made them so interesting. And the in-between phases between years (e.g. Manny Janitor to Manny Boss etcetera) were meant to be unexplained. It meant that you could see that Manny was indeed a smooth dealer which meant that he really was being screwed with at the DoD (Department of the Dead).
I think that if you had to do another game about Manny and friends, they would be back in the world of the living (the train having taken them back and of course they wouldn't remember their past lives/deaths). But people would have stopped dying as the DoD has stopped because of the events of the first game causing such a big shake up that the entire system broke down. Manny would slowly remember parts of his previous journey and would have to fix everything by figuring out all the problems and dying so he could return to and restart the DoD. Obviously drama, reunions and hi-jinks (possibly even zany ones) would occur. The game could take place in the world of the living (at first normal and boring but slowly becoming more and more creepy and bizarre as Manny remembers his past life) and the land of the dead (initially only seen in flashbacks and seeming dark and sinister but slowly becoming more bright and normal as time wears on).
That's a good point.
I'll counter it with a HURRRRRRRRRRRRRRRRRRRR!
Yes I am a bastard. I've worked long and hard for the right to be one and what would be the point if I didn't flaunt it?