Note that save game 1 is the auto-save slot, and it gets overwritten by whatever save game you loaded (as you play, the game autosaves at certain points). I can't remember if you get prompted to save when you select Quit, or if it auto-saves at that point, but from memory Sam & Max Season 1 episodes did not auto-save on quit.
I don't recall having to do anything with the cheese wheel other than making sure it has eyes, and rotating it to the correct place.
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