Wait, so NOTHING is click-able? I think that there is a button that highlights all items that are interactive, by pressing this you might be able to make everything click-able again (but that's a long shot). If this doesn't help at all, then you may just have to restart and save right before you sail out to McGillicutty's ship and just hope that the same problem won't happen twice. If that doesn't work, then you may have to ask some of the friendly people on the forums for a savegame file. If no-one helps you, then you may just have to watch xaeternax's ToMI playthrough on youtube so that you can view the ending of episode 2.
EDIT: Oh, sorry, you're using Wii. I guess the savegame file thing won't really be possible then.
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Read that instead ^.
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