Btw, I think we completely forgot about Murray. Why not make HIM the main villain this time? A skull with some attitude, saying to Guybrush: "Well, what do you say now, puny mortal? You thought all these times that I was just some skull unable to defend myself? Well, tremble before my new power MWAHAHAHAHA"
All this time we've been taking Murray too jokingly. If he would be reappearing causing some serious trouble I think that might actually work.
@hayden While I don't spurn the idea of giving LeChuck a break, I think removing him from the game completely is a tad too much. He's a trademark, and, well, he must be present at least in one episode and do some of his boring stuff, but putting him on par with another entity could actually work.