Plus, Hit the Road's voice acting, with no offence meant to the actors, just...isn't that good. They both sound pretty bored, the delivery of the jokes is flat and they get the context of their lines wrong.
In the comics, TV series, and Telltale series, Sam and Max to me always feel like two close friends who have known each other for a very long time. They have in-jokes, they bounce off each other, they know how to make each other smile. But in Hit the Road it's as if they just met, and they don't really seem to like each other that much. They don't have the same energy.
^ Thanks for reading that.