Without getting too in-depth/set-up-for-disappointment/fanfiction-y about it, did anyone else pick up on President Superball's line in 305 about his 'superiors'? It's probably a conspiracy theory gag, but I know I'm curious!
If they did go there, that would also have the benefit of, potentially, not being too far a step down from Satan and Elder Gods. You could do pretty much anything with that idea.
The only other idea I have is that, since Noir Sam was so popular, he'll show up again... which will probably mean something awful (but temporary) happens to Max.
ALSO I HAVE A GOOD FEELING IT WILL BE A POINT-AND-CLICK ADVENTURE GAME, GUYS.