Originally Posted by scutheotaku
I'm not sure about that specific error, but try ScummVM - it'll let you play CMI (and most other SCUMM games) on newer computers without much issue.
That's true, but ScummVM doesn't like the disc change in CMI, causing the game to crash, or the cut-scene for part 3 to have to be skipped.
Though you are right ScummVM is the way to go, just thought I'd also add, that you need to copy the files from your CMI CD's into a set file on your computer and run it from there (on ScummVM) this fixes the game completely. You need all the files from Disc 1 and only the files on Disc 2 that aren't included on Disc 1 or have 2 in there name. I suck at explaining, but there is a full explanation of how to do it online.
Hope that helps.