Originally Posted by Frostbyte
There are two things that are known to cause this problem:
1. Anything that causes the program to end suddenly (power failure, game crash, etc...)
2. Certain Video players corrupt the save files. If you're running video in the background you run the risk of losing data.
1) Meh. Now we just have to find out what causes a CTD. Weird.
2) Only video players? Nothing with audio player or embedded Flash Content playing?