I agree, there are many instances of frame-rate drops, choppy audio, and skips during the cut scenes.
I downloaded the game to my hard drive (no use of cloud storage or external USB). My Xbox is a slim/black one with the 250gb drive.
There are also numerous times that the game fails to plot an effective path between people when you're walking around. For example, when Kenny is pushing Duck on the swing, you can go over and talk to Clem.
If you try to talk to Kenny, Lee has to walk in front of Duck (towards the camera) to get to Kenny. But the game cannot plot a set of waypoints to make this work so Lee just keeps running into an invisible barrier in front of Duck.