Guybrush: Andrew Garfield
LeChuck: Anthony Hopkins
Elaine: Emily Blunt
Voodoo Lady: Queen Latifa
Stan: Robert Downey Jr.
Herman Toothrot: Tom Hanks
Carla: Halle Berry
Otis: James Franco
Meathook: Robert DeNiro
Wally: Warwick Davis
Captain Dread: Will Smith
Largo: Danny DeVito
Goodsoup: Michael Caine
Haggis: Mike Myers
Cutthroat Bill: Bob Hoskins
Van Helgan: Liam Neeson
Murray: Denny Delk (just use a CGI skull or puppetry, no physical actor necessary)
Ozzie Mandrill: Russell Crowe
Casaba: Christopher Walken
DeSinge: Sacha Baron Cohen
Morgan: Anne Hathaway
DeCava: Christian Bale
These selections are mostly based on how I can see them pulling off the roles, not necessarily voice or appearance.
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"There was an old farmer who lived on a rock,
he sat in the meadow just shaking his..."-The assumption song. A random youtube search can bring on a big laugh.
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