The real end of the new Homestar Runner content was actually last year. Matt Chapman was featured on the song Pink Pants by Aquabats as Strong Bad and Homestar on their 2011 album "Hi-Five Soup!".
He also brought the
Strong Bad puppet to the Aquabats concert in Atlanta, Georgia on the release day of that album (on the 18th of January).
Like unicornfoal said, the Chapmans been busy with their families and working on children's shows (Yo Gabba Gabba! and The Aquabats). I would be extremely surprised if they didn't release at least something Homestar Runner related by the end of the year. There hasn't been a year completely without new H*R stuff since it started.