The Carl Grimes panel sums it up. This is The Walking Dead. Shit just happens.
That said, from a storytelling standpoint, I'm also impressed with the way Telltale gets me to like previously unlikable characters just before killing them. I was starting to warm to Larry just before his demise. I was starting to love Duck before he got bit. If the next episode makes me like anybody that I don't already (like, say, Ben, Christa or Chuck) I'm going to automatically consider them doomed.