If I read his post correctly, he's talking about the early 2000's re-release that Activision put out in Europe. In that case, it might work. It uses Aaron Giles' Windows port (he made a bunch of ports of LucasArts adventure games to Windows before he left LucasArts, and LucasArts didn't bother re-releasing them until years later), and the Steam games also use Aaron's Windows ports, and they work in Windows 7.
However, you're still better off playing Sam & Max Hit the Road in ScummVM than in the original executable by LucasArts, as ScummVM fixes
a fairly major bug that causes the game to hang in the original executable.