Originally Posted by MattP
A new patch has been released that will resolve this issue. Please restart your game and you will be prompted to install the v1.03 patch.
Please note, if you received the corrupted save message and exited to the XMB (Sony dashboard), then you will need to rewind 1 checkpoint before continuing your game. If you have never received this message, or pulled down an unaffected save from cloud storage, you can continue your game as normal.
My PS3 is currently frozen behind me after my 2nd playthrough, properly frozen, no way back to the XMB without shutting the machine off, so I guess I'm stuffed. More annoying, I'm wondering why this wasn't auto-patched as soon as I started the game.