To quote a good song 'No safety or surprise, the end. I'll never look into your eyes...again'
Sometimes something is as thus presented. No surprise, no sudden safety from his fate, it is the end.
I took it as his end when the screen didn't transition screens, it didn't fade out, it simply dropped to black upon a silent screen. It was a clear sign to me that Lee had met his fate, seeing as he was the eyes of the player and that eye into the world was now gone.
I have Anatidaephobia