I would actually love seeing new people. One thing I really like in The Walking Dead game is that you see a new cast, a glimpse of what other people are dealing with outside of Rick Grimes. I wish that's what they did with the TV series, make a new cast instead of just loosely following Rick's story. Maybe then it would be canon.
One thing I would be extremely pissed about is if Clem isn't in season 2. I want to see how she developed after Lee's last words to her. Yeah yeah she can appear in like season 4 or something but I don't want to wait that long to see Clem. I want a merging of the old cast and a new cast. Omid / Christa, Molly, and Clem join a new group and you play as one of the characters in the new group.