I don't get an error message. The game just crashes to the desktop, and I get a dialog box that says, "Walking Dead 101.exe has stopped working, windows will search for a solution."
I have the Steam version of the game, and I'm running Windows 7 64bit. My PC has an i3 with 6GB of RAM and Nvidia GeForce GTS 250.
I haven't tried uninstalling and then re-installing the game yet.