I, too, as an audio engineer/audiophile, was stricken with some confusion when I heard the blatant audio compression artifacts on such a new game. I wonder what kind of compression is being used? Even a lower quality MP3 compression wouldn't yield such a strange sounding (quantization?) distortion. Also, don't most people have broadband connections these days? I downloaded the game in maybe 10 minutes, tops. Most MMORPG's take a few hours to an entire day to apply all the patches out of the box these days, so adding a few more megabytes onto the install package doesn't seem like it would offend too many people.
I sort of feel bad jumping on the "audio compression sucks" bandwagon, especially when I am so, otherwise, incredibly happy with the game. I've been waiting so long for another Sam n Max that it almost just doesn't matter. ...and the monthly episode thing? Fantastic idea. If I were a rich man I would donate generously to Telltale for their efforts in revitalizing the pc adventure genre. Keep it up.
In conclusion, I would be immensely appreciative of either an add-on speech pack, a larger install file, or a more transparent compression technique for the audio files. The music sounds great, though!
-jake