Noticeable bugs from my end was, the Next door neighbour and the flower in her hair glitches throughout the majority of the game, where as her head would move the flower would stay in place, or duplicate.
Upon the beginning of the second chapter wallace's face stayed in the

expression until I spoke with somebody.
The main menu of the game shouldn't have been graphic heavy, I would have suggested Telltale change the menus to be more ipad friendly, just for a smoother quicker experience.
There was a few obvious things such as frame rate, when entering or exiting a room, or when there is a lot going on screen (final chapter particularly)
Finally, the dress up box for the two dogs, one time I used it to select an item, but the 'tap here to exit' menu was not available, causing me to have to restart the game from my last save point.
This isn't to say I did not enjoy the game. The game itself is very enjoyable, you so long as you can accept that the iPAD is NOT a PC, then you can understand why ports like this will never be perfect. This is a big improvement over the first Sam and Max episode from what I have been reading, so I would assume that the quality of episodes will only get better with time with more releases. It's just good to see TellTale adopt this platform early in it's release. It's certainly put a smile on my face.
Again though, my main bit of advice for future releases would be to simplify the main menu graphics, there aren't an important part of the game so better to make them smoother and easily accessible than current.
I look forward to other releases. I imagine Puzzle Agent will run fantastically on iPAD considering it's art style etc..