Lee and Clementine might pop up. You never know. The TV show has basically said "fuck the comic canon" on occasion.
- We haven't even seen Lilly in Woodbury, instead we got the Haley chick who's probably a mashup of Lilly and someone else.
- We got the Dixon brothers, two totally new characters (that are awesome, by the way).
- Shane lasted longer than Sophia (who's still alive in the comics).
- Dale died earlier than Shane.
- Carol's still alive.
- Lilly/Haley didn't shoot Lori, Carl did.
- Judith is still alive.
- Tyreese was supposed to show up a lot sooner than he did.
So, for all we know, Lee could possibly make an appearance in the TV show, alive, with both his arms, lol. And so could Clem.
And the game is a force to be reckoned with. Amazing reviews and sales, so for the TV show creators to incorporate elements and characters from the game wouldn't be as unlikely as you think.