A high-tech laboratory.
Between dangerous chemistry, genetic manipulation and strange rays, there's plenty of fun to be had and plenty of opportunities for very good puzzles. It could also easily contain a mind-swapping device, allowing a part where you have to control Max (or at least his body). And it could contain everything you need to operate time- or dimension-travel.
Your immediate goal in the lab would be to use the peculiar tools it offers to bypass its high-tech security system, gradually gaining access to more and more of it. As for a more long-term reason, here's one suggestion: Bosco bought the lab from his ill-gotten gains, and has managed to lock himself in. The first puzzle might be to find and open the secret entrance to get into the lab at all.
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although we do still have a time machine, so I wouldn't completely rule out the possibility.
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